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Fenofibrate produces a reduction in amputation events in type II diabetics
May 2013
Fenofibrate produces a reduction in amputation events in type II diabetics
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Effect of fenofibrate on amputation events in people with type 2 diabetes mellitus (FIELD study): A prespecified analysis of a randomised controlled trial
Lancet. 2009 May 23;373(9677):1780-8Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
9795 patients with type II diabetes were randomized to receive daily treatment with 200 mg of fenofibrate or equivalent placebo treatment. This study examined the effect of a long-term lipid-lowering treatment on occurrence of amputation and reduction of adverse outcomes of the macro- and micro-vasculature. At 5 year follow-up, fenofibrate produced a reduction in non-traumatic amputations observed...
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