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Aceclofenac & Ilaprazole vs Celecoxib for NSAID-Induced Dyspepsia in Lumbar Spinal Stenosis Patients

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October 2023

Aceclofenac & Ilaprazole vs Celecoxib for NSAID-Induced Dyspepsia in Lumbar Spinal Stenosis Patients

Vol: 303| Issue: 10| Number:6| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy of Aceclofenac and Ilaprazole Combination Therapy versus Celecoxib Monotherapy for Treating NSAID-Induced Dyspepsia in Lumbar Spinal Stenosis Patients.

Medicina (Kaunas). 2023 Jul; 59(7): 1307.

Contributing Authors:
S Lee JG Kim HJ Kim

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Synopsis

128 patients with lumbar spinal stenosis who were receiving continuous non-selective nonsteroidal anti-inflammatory drugs (NSAIDs) were randomized to receive either a COX-2 selective NSAID (celecoxib; n=64) or a combination of an NSAID (aceclofenac) and a proton pump inhibitor (ilaprazole) (n=64). The primary outcome of interest was the severity of dyspepsia, as measured by the Short-Form Leeds Dy...

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