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Diacerein vs. NSAIDs for Knee Osteoarthritis: A Meta-Analysis
June 2023
Diacerein vs. NSAIDs for Knee Osteoarthritis: A Meta-Analysis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Diacerein versus non-steroidal anti-inflammatory drugs in the treatment of knee osteoarthritis: a meta-analysis.
J Orthop Surg Res. 2023 Apr 18;18(1):308.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
12 RCTs with a total of 1732 knee osteoarthritis patients were included in this systematic review and meta-analysis comparing diacerein (n=861) to NSAIDs (n=871) for symptom control. The pooled outcomes of interest included the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis index, pain on a Visual Analog Scale (VAS), global efficacy, and the incidence of adverse events. The resul...
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