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Pre- versus perioperative intravenous dexamethasone for analgesia in total knee arthroplasty

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Ace Report Cover
December 2018

Pre- versus perioperative intravenous dexamethasone for analgesia in total knee arthroplasty

Vol: 7| Issue: 12| Number:19| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

Multiple Doses of Perioperative Dexamethasone Further Improve Clinical Outcomes After Total Knee Arthroplasty: A Prospective, Randomized, Controlled Study

J Arthroplasty. 2018 Nov;33(11):3448-3454. doi: 10.1016/j.arth.2018.06.031

Contributing Authors:
FX Pei S Zhang J Xie Y Lei G Cao H Xu

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Synopsis

182 patients scheduled for total knee arthroplasty were randomized to either perioperative intravenous dexamethasone administration, including one dose preoperative and subsequent doses at 24 and 48 hours afterward, to a single preoperative intravenous dexamethasone infusion, or to no dexamethasone administration. Patients were assessed for pain scores, analgesic consumption, incidence of postope...

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